Cleaning validation is a process of providing documented evidence that the cleaning methods employed within a facility consistently controls carryover of product. The aim of the present study was to validate simple analytical method for verification of residual terazosinin equipment’s used in the production area and to confirm effectiveness of cleaning procedure. UV spectrophotometric method was developed and the detection was made at 245 nm. A cleaning verification assay was validated by using rinsing sampling technique. Recovery studies were carried out on stainless steel surface. The calibration curve was linear over a concentration range from 2 to 10 µg/ml with a correlation coefficient of 0.9992. Detection limit and quantitation limit was detected by UV visible spectroscopy as 0.01547 µg/ml and 0.0469 µg/ml. The developed UV spectroscopic method can be used successfully for routine analysis of terazosin residues on cleaned surface in production area.
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